The Aptamer Base is a collaboratively created knowledge base about aptamers. Aptamers are short sinlge stranded nucleic acids or amino acid polymers that recognize and bind to targets with high affinity and selectivity. Nucleic acid aptamers are tipically isolated from large combinatorial libraries through the application of SELEX. The Aptamer Base has been built on Freebase (a free openly licensed community built resource for structured data). Freebase organizes over 360 million facts into bases, collections of thematically related topics. The Aptamer Base is one such collection which contains expert curated descriptions of in vitro created sequences and related experiments.
You can access the Aptamer Base by using its web interface. If navigating the base is not enough for your needs, programmatic access to the data is also made available through Freebase's query editor. Read our tutorials on how to browse, query, add and download data from the Aptamer Base.
The open nature of the Aptamer Base is one of its key features, and as such we invite the community to help us in the process of adding, curating and using this information. Currently the Aptamer Base reuses several types and topics already found in Freebase. In turn, our types and topics are currently being used by members of the Freebase community. For more details see our Documentation page.